Search results for "Block structure"
showing 2 items of 2 documents
An FPGA aligner for short read mapping
2012
The rapid growth of short read datasets poses a new challenge to the mapping of short reads to a reference genome in terms of sensitivity and execution speed. In this work, we present a parallel architecture for short read mapping utilizing field programmable gate array (FPGA)-based hardware. The computation intensive semi-global alignment and the hash table lookup operations are mapped onto an FPGA. The proposed Align Core is implemented with a parallel block structure to gain computational efficiency. We present a new parallel block-wise alignment structure to approximate the conventional dynamic programming algorithm. The performance of our FPGA aligner is compared to the GASSST and BWA …
Template-synthesized nanostructure morphology influenced by building block structure
2011
We report the synthesis and characterization of a series of nanostructures and determine whether several distinct types of building blocks can be fashioned into linear nanostructures using hard-templates and electrochemical methods. We determine the aspects of molecular structure that influence morphology and propose a mechanism whereby morphology changes as a function of building block. We show how hydrophobic side-chains, such as 3-hexyl and 3-(2-ethyl)hexyl, can be used to prepare nanostructures with a geometry that is different from the shape of the template from which they derive. These nanostructures exhibit collapsed, nonlinear, and nonrigid shapes as observed by SEM and TEM. Hydroph…